Longitudinal Study of Alzheimer's Disease Degeneration through EEG Data Analysis with a NeuCube Spiking Neural Network Model

Motivated by the dramatic rise of neurological disorders, we propose a SNN technique to model electroen-cephalography (EEG) data collected from people affected by Alzheimer's Disease (AD) and people diagnosed with mild cognitive impairment (MCI). An evolving spatio-temporal data machine (eSTDM), named the NeuCube architecture, is used to analyse changes of neural activity across different brain regions. The model developed allows for studying AD progression and for predicting whether a patient diagnosed with MCI is more likely to develop AD. © 2016 IEEE.